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Amphetamine is thought to inhibit monoamine oxidase, whereas the power of amphetamine and its metabolites to inhibit a variety of P450 isozymes and also other enzymes has not been sufficiently elucidated. In vitro experiments with human microsomes point out small inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by on